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Research Scientist (m/f/d) for optimization of nucleic acid structures

Posted on Feb 1, 2019 by AGCT GmbH

Marburg, Hessen Germany
Health Care
14 Jan 2019
Annual Salary
Full-Time
AGCT is a diagnostics start-up with an experienced team of researchers, laboratory physicians and engineers. We focus on the development of a new technology to enable next-generation DNA assays for pharmaceutical research in oncology and future clinical practice. Our proprietary cyberPCR technology enables us to design test systems with unmatched performance parameters that run smoothly on existing PCR lab equipment and are cost effective.
We are currently looking for a(Senior) Research Scientist (m/f/d)
to join our R&D team. Someone with exceptional drive and passion, who will help shape the development of our innovative assay technology for the oncology market.
Research Scientist (m/f/d) for optimization of nucleic acid structures
(location: Marburg site, permanent full-time position) Activities and responsibilities Tasks and responsibilities
Designing, prototyping, testing and optimization of nucleic acid structures to improve our amplification technology
Investigating structure-function relationships and evaluating new nucleic acid amplification chemistries
Analyzing scientific results, troubleshooting methods and devising creative solutions
Independent planning and implementation of analytical and research activities
Qualification profile Minimum Qualifications
PhD in life sciences/chemistry or related field plus a minimum of three years industry or post-doctoral experience
In-depth experience with nucleic acid-based assays, quantification, and modification methods
Outstanding analytical thinking and enthusiasm for hands-on bench work have been keys to your success
Ability to simultaneously handle multiple challenges with structured, analytical and solution-oriented thinking
Fluency in English, basic German knowledge is considered advantageous.

Preferred Qualifications
Strong background in ideation proven by a publication record in fields such as
Dynamics of nucleic acid structures, branch migration, modified nucleic acids design, fine tuning of intra- and inter-molecular interactions in the field of nucleic acids
Engineering and design of nucleic acid structures: e.g. nucleic acid-based switches, Ribozyme, DNA-Origami, RNA-Folding, Aptamers, CRISPR/Cas, probe, nucleic acid-based programmable sensors)
In-depth design and characterization of probe-based methods (e.g. FRET, qPCR, TaqMan, Molecular Beacons)

Reference: 629200601

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