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Senior Scientist (m/f/d) Tau Biology in Neuroscience Discovery

Posted on Apr 6, 2019 by AbbVie Deutschland GmbH & Co. KG

Ludwigshafen am Rhein, Rheinland-Pfalz, Germany
Research & Development
4 Apr 2019
Annual Salary
Full-Time
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed
in 2013 following separation from Abbott Laboratories. The company's mission is
to use its expertise, dedicated people and unique approach to innovation to
develop and market advanced therapies that address some of the world's most
complex and serious diseases. AbbVie employs approximately 30,000 people
worldwide and markets medicines in more than 170 countries.

For our location in Ludwigshafen, Germany we are looking for a

Senior Scientist (m/f/d) Tau Biology in Neuroscience Discovery

REF:

JOB DESCRIPTION

The position is located within the Tau Biology Group in the Neuroscience
Discovery organization at Ludwigshafen. The accomplished neurobiologist will
make substantial contributions to the conception and execution of new
therapeutic approaches to neurodegenerative diseases in a collaborative
environment. A primary responsibility of the successful candidate will be to
develop and execute cellular and ex vivo models of Tau pathology with a focus
on Alzheimer Disease and other tauopathies. Experience with protein
biochemistry, proteomic, molecular and cellular biology, microscopy and
enzymatic assays would be an asset.

Key Objectives

* Independently design, execute, analyze and interpret experiments to address
key scientific questions.
* Independently perform data analysis and interpretation and presentation of
in vivo, ex vivo and in vitro experiments.
* Contribute to identify new targets, design and execute target validation
studies.
* Plan and coordinate complex experiments involving interdisciplinary working
groups.
* Design, establish and validate cellular and ex vivo models for Alzheimer
Disease.
* Identify, develop and optimize new techniques to address critical project
needs.
* Effectively compile and present scientific plans and data.
* Read and apply relevant scientific literature to support scientific
discussions.
* Collaborate with other groups in discovery, developmental sciences and
global colleagues. Education and qualification:

* PhD or MSc in neuroscience, cell biology, biochemistry, pharmacology or
related field with at least 2 years of postdoctoral or equivalent industrial
experience. Experience in drug discovery would be an advantage.
* Track-record in neurodegenerative diseases would be desirable.
* Expertise in protein biochemistry, molecular and cellular biology,
including method development and validation.
* Expertise with culturing primary neurons and/or iPSC-derived neurons and
their genetic manipulation.
* Knowledge on relevant transgenic mouse models of Alzheimer Disease. Basic
knowledge in tissue harvesting and dissection.
* High scientific rigor and commitment to provide robust, high-quality
scientific results.
* Very good skills in planning and coordination of complex interdisciplinary
studies.
* A high degree of self-initiative, independency, flexibility and curiosity.
* Excellent teamwork and interpersonal relationship skills.
* Good communication skills and proficiency in English (written and oral).
* Ability to present scientific activities/results at internal and external
meetings, and publish in peer-reviewed journals We offer you

* An opportunity to work in a world-class team
* A supportive environment that allows you to focus on your role and tailor
your work to your individual needs, includingflexible work models, multiple
benefits, and comprehensive health and sports programs
* Attractive compensation and company benefits, including our excellent
occupational health management system, which is one of the best in Germany YOUR
APPLICATION

We are looking forward to your online application

. Please provide information about your salary expectations and possible start
date in your motivation letter.

An equal opportunity employer. AbbVie welcomes and encourages diversity in
our workforce.

Learn more about AbbVie Deutschland at

. Visit

for more information about the therapeutic areas in which we're active.

PEOPLE. PASSION. POSSIBILITIES.

Reference: 687899149