Senior Scientist (m/w/d) Proteostasis Biology Area

Posted on Apr 17, 2019 by AbbVie Deutschland GmbH & Co. KG

Ludwigshafen am Rhein, Rheinland-Pfalz Germany
Research & Development
16 Apr 2019
Annual Salary
Full-Time
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed
in 2013 following separation from Abbott Laboratories. The company's mission is
to use its expertise, dedicated people and unique approach to innovation to
develop and market advanced therapies that address some of the world's most
complex and serious diseases. AbbVie employs approximately 30,000 people
worldwide and markets medicines in more than 170 countries.

For our location in Ludwigshafen, Germany we are looking for a

Senior Scientist (m/w/d) Proteostasis Biology Area

REF:

JOB DESCRIPTION

For the Proteostasis Biology Area in Neuroscience Discovery we are seeking an
experienced researcher for a bench scientist position. This is an excellent
opportunity for a scientist interested in protein homeostasis, misfolding and
degradation in the context of neurodegenerative diseases applying
state-of-the-art technologies to enable the development of future medicines in
the field of neurology.

YOUR RESPONSIBILITIES

* Develop, optimize & execute relevant experimental approaches to
support drug discovery & development programs in the field of
Alzheimers and Parkinson's disease research
* With excellent scientific background and through direct experimental
contributions at the bench, provide critical information for drug discovery
projects
* Generate and analyze cellular and biochemical data sets; interpret own
experimental results to support the understanding of the disease guided by
strong knowledge of neuroscience
* Develop and execute biochemical and cell-based assays to validate novel
targets in the proteostasis area, focusing on autophagic and proteasomal
clearance mechanisms
* As a member of an interdisciplinary team, work together with cellular and
molecular biologists, in vivo pharmacologists and medicinal chemists, also
across global research sites
* Present research activities / results at internal and external meetings,
and publish in peer-reviewed journals YOUR QUALIFICATIONS

* Ph.D. or M.Sc. degree in Biology, Biotechnology, Pharmacology or related
field with at least 3 years of postdoctoral or equivalent industrial experience
(8 years of experience for an M.Sc)
* Hands-on experience in developing enzyme assays, cellular assays; knowledge
of protein analytical technologies (e. g. immunoprecipitation, Western
blotting, WES), molecular biology and cell culture (also transfection /
transduction of clonal and primary cells)
* Track-record in autophagy or other proteostasis-related research, and
scientific background in neurodegenerative diseases
* Expertise in developing imaging assays and approaches to detect
protein-protein interactions (high content imaging, proximity ligation assays)
is a plus
* Experience obtained in the biotech or pharmaceutical industry is highly
desirable
* Highly motivated and self-driven, with great communication and presentation
skills, excellent team player
* Fluency in English We OFFER you

* A fantastic opportunity to work in a world-class team
* A mentor who will assist you as coach and contact person
* A supportive environment that allows you to focus on your role and tailor
your work to your individual needs, including flexible work models, multiple
benefits, and comprehensive health and sports programs
* Attractive compensation and company benefits, including our excellent
occupational health management system, which is one of the best in Germany YOUR
APPLICATION

We are looking forward to your online application

. Please provide information about your salary expectations and possible start
date in your motivation letter.

An equal opportunity employer. AbbVie welcomes and encourages diversity in
our workforce.

Learn more about AbbVie Deutschland at

. Visit

for more information about the therapeutic areas in which we're active.

PEOPLE. PASSION. POSSIBILITIES.

Reference: 694537291

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