Senior Scientist, Molecular Technologies
Posted on Apr 5, 2021 by Seres Therapeutics, Inc.
The Senior Scientist, Molecular Technologies will drive the development and implementation of both classic and novel molecular and genomics methods to support the discovery and development of microbiome therapeutics.
What Youll Do
Oversee the design, development, qualification, and execution of molecular-based assays to support the characterization of complex microbial communities and defined compositions of microbes as well as molecular characterizations of host response to microbiome perturbations.
Develop and use qualitative and quantitative assays to define parameters of sample preparation and NGS library construction steps for a broad range of clinical and non-clinical samples.
Work directly with our bioinformatics and microbiome sciences groups to understand how various sequencing methodologies and library construction workflows directly impact gut microbiome characterization and our in-house data analysis pipelines.
Work both internally and externally with vendors as a subject matter expert in the field.
Integrate closely with the Molecular Technologies team on collaborative projects; sample or data hand-offs; and shared laboratory, planning, and tracking activities.
Collaborate closely with the Molecular Technologies, Computational Microbiome Sciences, Bioinformatics, Clinical, and Quality groups to develop, prototype, and qualify molecular- and genomic-based QC and clinical assays.
Stay current with literature to enable the company to stay abreast of the most recent developments in genomic and other relevant methods for the characterization of microbial strains and communities.
Represent Molecular Technologies in cross-functional R&D program, platform, or incubator teams.
What Youll Bring
5+ years post-graduate experience developing and performing molecular techniques, including but not limited to short-read sequencing (eg Illumina) and/or long-read sequencing (ONT or Pacbio), PCR/qPCR, Nanostring, FISH, or similar assays, preferably in a biotech or pharma setting.
Experience working with and/or integrating laboratory automation to scale up molecular processes preferred.
Demonstrated strong organizational and interpersonal skills, effective communication skills, rigorous quantitative approach, and keen attention to detail
Enthusiasm for a team-driven mindset in a diverse and dynamic environment
Ability to work independently and take initiative in a highly dynamic environment
Previous management/supervisory experience a plus.
Ph.D. in Molecular biology, Biochemistry, Microbiology, or a related field