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Principal Scientist Translational Immunology

Posted on Apr 5, 2021 by Bristol-Myers Squibb

Princeton, NJ 08540
Immediate Start
Annual Salary

Job Description
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.


Bristol Myers Squibb is a leading global biopharma company focused on discovering, developing and delivering innovative medicines for patients with serious diseases. We are focused on helping millions of patients around the world in disease areas such as oncology, hematology, immunology, cardiovascular and fibrosis. Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative results.

The Immunology, Cardiovascular and Fibrosis Thematic Research Center (ICF TRC) is focused on discovering and developing novel therapeutics to treat inflammatory, cardiovascular and fibrotic diseases. The Translational Early Development group within the ICF-TRC is seeking a creative, thoughtful, and highly motivated immunologist to join our vibrant and cohesive team. Together, we will generate hypotheses for patient segmentation, develop critical assays to evaluate target engagement and pharmacodynamics of our new drugs in patients, and provide a better understanding of target biology in disease.

Elements of the position:

Being a thought leader within the team to critically evaluate the literature regarding target and disease biology
Independently design, execute and interpret series of experiments to generate data to support decision making. Support scientific associates in design, execution and interpretation of experiments.
Introduce and troubleshoot new methods, platforms and project concepts.
Represent the Translational Early Development group on project teams and deliver on translational research needs
Provide operational oversight of specified instrumentation
Maintain an accurate electronic notebook and comply with laboratory safety procedures
Process and communicate scientific findings in joint meetings and in written reports or manuscripts
Scientific management of collaborations with academic or industry partners

The successful candidate will be expert in immunology, demonstrated through authorship/co-authorship of peer reviewed publications and substantial post-doctoral academic/industry experience with evidence of sustained high performance and accomplishment
Thorough knowledge of experimental design, and a high level of technical laboratory skills (including cell culture, immunoassays, protein signaling, qPCR technology platforms, high parameter flow cytometry and imaging) together with an ability to interpret results
Experience with managing and mentoring direct reports preferred
Experience with collaborative interactions with academic and industry partners
Excellent communication skills and ability to present data
Willingness to work in a highly collaborative cross functional research team environment
Skills/Knowledge Required:

Ph.D. in a scientific discipline that relates to Immunology.
At least 5 years' post-graduate experience (academic post doc and/or industry experience).
Considerable laboratory expertise that spans molecular and cellular research as exemplified by research publications and/or patents.
Deep knowledge of human immunology and autoimmune diseases
Experience with mining large datasets, either independently or in collaboration with bioinformaticians to understand disease pathophysiology and/or establish patient segmentation hypotheses
Clear evidence of sustained independent thought and creativity in developing and implementing advanced technology and ideas to answer key translational questions.
Strong leadership, communication and problem-solving skills, and experience in participating in and/or leading multi-disciplinary project teams.
Ability to collaborate in teams and work with others in a matrixed environment, and manage multiple workstreams simultaneously
Skill in managing external collaborators and setting clear timelines and expectations
Knowledge of supervision and development of scientific employees. Skilled in applying that knowledge to optimize the performance of those supervised

Reference: 1152695278

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