Scientist/Research Investigator

Job Description
Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist/Research Investigator, in our Cambridge, MA office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

POSITION OBJECTIVES:

Scientist/Research Investigator is responsible for cell line development activities including transfection, cell culture maintenance, clone selection, and genetic engineering and characterization of mammalian cell lines for clinical and commercial production. This may include performing laboratory experiments using a variety of molecular biology and cell culture technologies. This position also will optimize current process and develop new methods and technologies to improve platforms and processes.

POSITION ACCOUNTABILITIES:

Employs molecular biology methods for cell line engineering and improvement

Performs phenotypic and genotypic characterizations of the cell lines

Works with departmental and/or cross functional peers to execute on assignments under limited supervision.

Interprets data independently, identifies technical issues and implements solutions under limited supervision

Contributes to the design of new applications and operations in consultation with supervisor; evaluates new technologies and participates in new platform development

Documents experimental procedures with electronic notebook and authors CLD reports for regulatory filings

Presents study results in internal meetings, participates in project meetings/decisions

The candidate will need strong skills with MS Word, Excel and PowerPoint to organize and document experimental procedures with electronic notebook and to prepare reports

EDUCATION, EXPERIENCE AND SKILLS:

Education Requirements

Ph.D. in biochemistry, biology, biotechnology, or related pharmaceutical science

Master's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 5+ year of biotechnology/biopharmaceutical industry experience in cell line development

Bachelor's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 7+ years of biotechnology/biopharmaceutical industry experience in cell line development

Previous experience in cell culture and aseptic techniques is required

Previous experience with molecular biology is highly desired

Previous experience in CLD technologies including culture of mammalian cells, single-cell cloning, clonality assessment, and clone screening is a plus

TECHNICAL REQUIREMENTS

Previous experience in cell culture and aseptic techniques is required

Previous experience in CLD technologies including culture of mammalian cells, single-cell cloning, clonality assessment, and clone screening is highly desirable

Analytical and Problem-Solving Skills - Ability to troubleshoot and resolve critical and routine issues using appropriate information

KNOWLEDGE AND SKILLS

Teamwork - Ability to work within department groups/team

Organization - Ability to manage work load efficiently and in timely manner especially when projects are at a critical stage

Technical - Proficiency in use of applicable lab equipment and operations; experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic)

Communication - Ability to report data, present findings to management

Computer experience in common Microsoft applications (Word, Excel, PowerPoint) is required

TRAVEL REQUIREMENTS

Minimal Travel, 0-5%