Process Development Associate Scientist - Cellular Sciences/Critical Reagents
Posted on Apr 6, 2021 by Amgen
WHAT YOU WILL DO
Let's do this. Let's change the world. In this vital role you will serve our global Amgen network with the creation, inventory and distribution of critical reagents required for characterization, in-process and release testing of Amgen biological products.
You will work with a small team of outstanding scientists to lead and support the purification and conjugation of antibodies and proteins used in Immunoassays, bioassays, the creation and characterization ready-to-plate bioassay cell banks as well as technology development efforts to continuously improve existing processes
Purification of monoclonal and polyclonal antibodies and conjugation of proteins using resin-based technologies and HPLC instruments,
Characterization of Critical Reagents utilizing Biacore, 2D gel and western blots and preparation of Certificates of Analysis
Creation and characterization of adherent and suspension cell lines to build robust and high quality cell banks for use in Quality Control cell-based bioassays
Management of a sophisticated inventory database and inventory forecasting and planning
Assess, develop and implement process improvements for generation and inventory management of all critical reagents
Communicate effectively and efficiently with cross-functional team members, clients and partner organizations
WHAT WE EXPECT OF YOU
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a hardworking and highly motivated scientist with these qualifications.
Master's degree and 2 years protein biochemistry, cell biology or molecular biology experience
Bachelor's degree and 5 years protein biochemistry, cell biology or molecular biology experience
Strong hands-on experience in antibody purification and cell culture/cell biology techniques, protein conjugation,
Candidate should demonstrate the ability to understand, apply, and evaluate principles of protein chemistry and cell biology.
Detail oriented and excellent documentation skills; Demonstration of proficiency in digital data analysis and visualization
Experience in digital inventory database management
Strong and broad skills using the tools and techniques of Project Management; specifically, knowledge of SharePoint and Smartsheet. Successfully manages multiple projects from conception through completion
Innovation and complexity: Make changes in systems and processes to solve problems or improve effectiveness of job area.
Communicates effectively with others, using appropriate diplomacy and sensitivity; makes others feel respected, valued and understood; works well in teams
Advanced scientific/technical reading/writing skills, advanced scientific analysis skills, and advanced laboratory work skills