Post-Doctoral Fellow, Immunogenicity
Posted on Apr 6, 2021 by Boehringer Ingelheim
Boehringer Ingelheim is currently seeking a driven and innovative Postdoctoral Scientist in immunology to join our Drug Metabolism and Pharmacokinetics (DMPK) Department at our Ridgefield, CT facility.
The DMPK Department is currently recruiting a postdoctoral scientist to further our mechanistic understanding of unwanted immunogenicity against novel biotherapeutic modalities, such as antibody-based scaffolds and viral gene delivery vectors. Information obtained from these investigations may drive sound decision-making for de-risking immunogenicity in the clinic. The candidates will collaborate cross-functionally, while focusing on aspects relevant to specific innate and humoral immune responses using in vitro, ex vivo and in vivo approaches. The scientist will be expected to initiate, present, and publish research findings in internal and external scientific communities.
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheims high regard for our employees.
Postdoctoral Research Areas of Focus in DMPK:
Explore/develop in vitro, ex vivo and in vivo experimental systems to characterize immunogenic potential/responses of biologic modalities.
Develop state-of-art technologies to characterize serologic and molecular properties of anti-drug antibody responses.
Deepen the understanding of attributes that affect innate and adaptive immune responses of antibody-based molecules and viral vector therapeutics.
Desired Experience, Skills and Abilities:
Recently granted or anticipated PhD degree in immunology or related field
Demonstrated knowledge of experimental immunology, such in vivo models, cell-based immune assays, ELISA, surface plasmon resonance and antibody characterization assays.
Ability to collaborate with scientists from other areas
Exceptional written and oral communication skills