Director Myeloid Asset, Translational Medicine
Posted on Apr 6, 2021 by Bristol-Myers Squibb
Job Description
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
POSITION
Director Myeloid Asset, Translational Medicine
SUPERVISOR
VP/Myeloid Disease Lead
LOCATION
Summit, NJ
DEPARTMENT
Translational Development
PREREQUISITES
Education: M.D/Ph.D.
Experience: 10+ years industry/academic research experience
Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.
Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.
Translational Medicine at BMS
Translational medicine is a department within the Research and Early Development organization that facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage translational development activities enable rational determination of dose-schedule and responsive patient populations, based on deep understanding of drug mechanism of action and disease segments. Late-stage translational development activities build upon the early work, additionally exploring mechanisms of resistance, rational drug combinations and product differentiation. The late-stage translational development function is responsible for the development of translational strategies to support the development, and maximize the potential, of BMS's therapies post-clinical proof-of-concept, including registrations and life-cycle management. Translational disease strategies in heme malignancies are derived from long term investments in developing data and deep expertise in disease biology, patient segments, immunodeficiencies and of therapeutic resistance to assist science driven strategies for the development of the heme pipeline.
Position Description:
Leads translational disease strategy in Myeloid disease area with deep disease, drug development and business knowledge
Leads and oversees execution of disease/asset strategy including but not limited to various aspects of patient selection strategies
Manages cross functional disease project teams with key interfaces in IT, IPS, data sci, Stats, external collaborators, contractors, other disease strategy leads and asset leads
Maintains relationship with translational clinicians for identifying new opportunities and for gaining disease insight
Develops and manages annual budget for Myeloid pipeline projects
Identifies needs, gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in Myeloid area
Serves as needed as translational representative on Disease Strategy Team/TRC teams and interfaces with commercial, clinical, Project leadership and regulatory teams to define patient segments of unmet need based on rapidly evolving clinical programs and commercial landscape
Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
Qualifications:
Ph.D in biological sciences with 12+ years experience
Deep disease and drug development knowledge, especially in Myeloid space
Immunology expertise is a plus
General understanding of preclinical research and clinical drug development
Management experience with the ability to set priorities, direct projects and implement complex strategies and work on cross-functional teams
Highly effective teamwork and interpersonal skills and the ability to work across numerous scientific disciplines
Able to communicate in both written and verbal format complex and detailed information in a manner that enhances understanding and ensures that the recipient will be able to apply the information presented.
Reference: 1152693381