Senior Associate Scientist, Cell-Based Assay

Job Description

Janssen Research & Development, L.L.C., a division of Johnson & Johnsons Family of Companies is recruiting for a Senior Associate Scientist, Cell-Based Assay in the new Lead Evaluation and Cellular Pharmacology team located in La Jolla area of San Diego, CA

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Discovery Technologies and Molecular Pharmacology team is a critical part of the Discovery Sciences organization in Janssen R&D and is committed to the delivery of high-quality chemical leads and clinical compounds in all five Janssen Therapeutic Area discovery teams. This mission requires deep scientific expertise in multiple fields including cellular pharmacology, chemistry, and screening technologies coupled with an ability to work collaboratively with internal and external partners.

In This Exciting Role, You Will:

Learn and apply state-of-the-art drug discovery approaches in a multidisciplinary team!

Develop, trouble-shoot and validate functional, cell-based assays

Profile compounds to enable medicinal chemistry SAR studies

Collaborate across multiple therapeutic teams and functional areas

Analyze data and present results at program team meetings.

Attend and present data at in-house seminars and external scientific conferences.

Publish research in high-quality journals, as appropriate.

Qualifications

Education:

Bachelor's degree in biochemistry, cell biology, or related field with at least 9 years of industry (pharmaceutical, biotech, and/or CRO) experience is required

OR

Master's degree in biochemistry, cell biology, or related field with at least 6 years of industry (pharmaceutical, biotech, and/or CRO) experience is required.

Required:

Experience using state-of-the-art cell-based assays is required

Extensive experience with cell culture and generation of stable cell line is required

Expertise with HTRF, luminescence and fluorescence-based assays in HTS format (384 or 1536 well) is required

Excellent written communication, verbal communication, and oral presentation skills are required

Preferred:

Proficiency with CAS/CRISPR genomic editing and RNAi approaches is preferred

Expertise with Fluorescence Flow Cytometry is preferred

Expertise with laboratory automation and high-throughput screening is preferred

Expertise in immunology, cardiovascular, infectious diseases, neuroscience and/or oncology therapeutic areas is preferred

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability