Senior Director, Compound Development Team Leader
Posted on Apr 6, 2021 by Johnson & Johnson
At Janssen Immunology, our vision is to restore health for the millions of patients living with immune disease. Our approach to achieving this aspirational vision is systematic and evidence-driven. We start with deep insights to unmet medical needs. We then align distinct immune pathways insights against these unmet needs. Our ultimate goal is rebalancing the immune system to achieve long-term remission. With unrivaled insights into the diseases of greatest unmet need and actionable science, we have established an industry-leading Immunology portfolio.
The late lifecycle CDTL leads a cross-functional Matrix compound development team to maximize the value of the asset and drives execution of the compound strategy when it reaches the end of its lifecycle. The CDTL champions the project(s) at all levels of J&J through providing clear communication, creative strategic approaches to development and securing appropriate resources.
Responsibilities include but are not limited to:
Lead the development and execution of the compound development strategy for the program(s), creating a vision for each compound within the TA portfolio, including identifying potential indication to be pursued and sequencing of these indications.
Lead the Compound Development Team (CDT) with representation from appropriate functional partners, to create a Development plan that provides a thorough and clear asset strategy by:
Integrating input from all functional areas to identify key development issues and the strategic approach to each, with associated timelines and budgets and providing clarity on alternative pathways and tradeoffs considered.
Creating the target product profile in collaboration with commercial, market access, medical affairs and clinical groups and adjusting this profile as new information and insights are gained.
Driving decision-making on compound late lifecycle strategy, ensuring relevant research, analysis, competitive data, and expertise are taken into account.
Leading discussions at the CDT to reach decisions, including making final decisions when full consensus cannot be reached.
Challenging functional representatives to ensure that all issues and questions are being addressed, and that functional area input into the strategy is adequate to meet the needs of the compound.
Managing the complexity of internal/external development and commercial activities and proactively identifying issues and risks while leading contingency planning and problem solving.
Ensuring development and implementation of optimal IP, medical affairs, publication and regulatory strategies to protect and maximize asset value.
Collaborating closely with the PML on the asset to identify and plan fit-for-purpose resources (FTEs and budget) to support the program.
Ensuring adequate project resource utilization and budget management, providing clarity and transparency on changes and potential tradeoffs.
Mentoring and coaching assigned team members to lead sub-teams and other Development Programs as required.
Ensuring team alignment with Leadership and executing on feedback with regard to Go/No Go decisions, timelines, key activities, resource allocations and budgets, valuations and prioritization.
Driving strategic alignment for development, medical affairs, commercial, pricing & market access plans.
Presenting strategic options and leading phase transition proposals at governance boards.
Maintaining a focus on pipeline value rather than single project value and balancing the role as team leader with a commitment to maximizing portfolio value by supporting Go decisions and appropriately arriving at No Go decisions.
Playing an active role as a member of the CDTL community to helping lead and devise strategies for key strategic initiatives and talent development across the Portfolio.
Representing the CDT on various cross functional committees.
Leading cross functional/therapeutic area/company initiatives outside of assigned CDT.
Participating in portfolio/strategy committees within the DAS/TA.
Deep understanding of the unmet need addressed by the asset; scientific/disease areas expertise as well as expertise in current and innovative therapeutic development paradigms
Ability to integrate all cross functional disciplines into a successful strategy
Deep understanding of requirements for successful commercialization of a new product, including competitive and payer landscape across different geographies and pricing strategies
Strong problem-solving skills for developing creative solutions and meeting project objectives
Influence, negotiation and conflict resolution skills, including the ability to influence without clear reporting authority
Ability to identify and manage all stakeholders, including at the most senior levels in the organization
Demonstrated ability of strategic thinking and contingency planning
Strategic Agility: Understanding big picture for compound and Janssen portfolio, translating scientific and business concepts into short and long-term deliverables, managing ambiguity and making decisions with incomplete data
Advanced Degree (Ph.D., M.D., Pharm.D.,) with at least 10 years of pharmaceutical industry experience is required
Experience in a leadership role as part of a research-driven pharmaceutical company is required
Experience in cross-functional team leadership, including strategy development and driving tactical delivery of programs
Experience with clinical development in Immunology is preferred
Alliance management experience is preferred
Demonstrated influence, negotiation and conflict resolution skills, including the ability to influence with clear reporting authority are required
Outstanding leadership, influence, and communication skills are required