Associate Scientist - Cell Therapy
Posted on Apr 14, 2021 by AstraZeneca
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Summary of the group:
The Cell Culture and Fermentation Sciences Group is accountable for cell line development, process development, and process characterization. This group assists in the scale up and technical transfer of processes to different clinical and commercial sites and also supports manufacturing deviations and regulatory submissions as needed.
Main Duties & Responsibilities:
Design and execute lab experiments to support CAR-T process development with minimal guidance; Use knowledge of immunology, cellular engineering, and T cell biology to improve CAR-T cell culture process;
Record, interpret and report experiment data in a clear and concise manner and communicate results to team members; demonstrates scientific rigor in assessing own data and that of others;
Present experimental results at internal and external meetings; author and contribute to scientific publications, patents, and regulatory submissions;
Work effectively and collaboratively as a team member within a highly matrixed organizational structure;
Education & Experience Requirements:
BS/MS in Chemical/Biochemical Engineering, Biotechnology, Biochemistry, Cell Biology, Immunology or Biological Sciences.
AS I: BS 5+ years of experience; MS 2+ years of experience;
AS II: BS 8+ years of experience; MS 5+ years of experience;
Understand cell culture and have mammalian cell culture process development experience in pharmaceutical company;
Experiment design and data/statistical analysis;
Excellent teamwork and communication skills;
Experience with CAR-T process development;
T cell culture and engineering;